Project Title:

Systematic Review on the Efficacy and Effectiveness of Chinese Medicine (CM) Intervention for Cancer Palliative Care
中醫治療於癌症舒緩治療的功效和有效性的系統評價

Principal Investigator:

Dr Vincent CHUNG

Organization:

Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong

Start Year:

March 2013 - February 2014

Status:

Completed 

Type of Study:

Systematic Review

Summary:

Background

Acupuncture and related therapies like moxibustion and transcutaneous electrical nerve stimulation are often used in managing cancer related symptoms but their effectiveness and safety is controversial. 

Methods

In this overview of systematic reviews (SRs), seven databases were searched from their inception till July 2014. We included SR that synthesized results from clinical trials on patients diagnosed with any type of cancer, and had received acupuncture and related therapies as supportive or palliative care. The Methodological Quality of Systematic Reviews (AMSTAR) Instrument was used to assess the methodological quality of included SRs.

Results

Twenty-three SRs were included in this overview. Methodological quality of included systematic reviews was satisfactory. Favorable therapeutic effects in managing cancer related fatigue (CRF), chemotherapy induced nausea and vomiting (CINV), and leucopenia among cancer patients have been reported. Conflicting evidence exist for the treatment of cancer related pain, hot flashes and hiccups; as well as in improving quality of life. Current available evidence is insufficient to support or refute the potential of acupuncture and related therapies in managing xerostomia, dyspnea and lymphedema, and in improving psychological well-being. No serious adverse effects were reported in all included studies.

Conclusion

Acupuncture and related therapies have demonstrated favorable therapeutic effects in managing CRF, CINV, and leucopenia among cancer patients. As acupuncture appears to be a relatively safe treatment, it could be considered as a complementary form of cancer palliative care, especially for clinical problems where limited choices were available from conventional care. 

Reference:

1) Chung VC, Wu X, Hui EP, Ziea ET, Ng BF, Ho RS, Tsoi KK, Wong SY, Wu JC (2015). Effectiveness of Chinese herbal medicine for cancer palliative care: overview of systematic reviews with meta-analyses. Sci Rep. 5:18111. doi: 10.1038/srep18111.

2) Wu X, Chung VC, Hui EP, Ziea ET, Ng BF, Ho RS, Tsoi KK, Wong SY, Wu JC. (2015). Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews. Sci Rep. 5:16776. doi: 10.1038/srep16776.

3) Chung VC, Wu X, Lu P, Hui EP, Zhang Y, Zhang AL, Lau AY, Zhao J, Fan M, Ziea ET, Ng BF, Wong SY, Wu JC. (2016). Chinese Herbal Medicine for Symptom Management in Cancer Palliative Care: Systematic Review And Meta-analysis. Medicine (Baltimore). 95(7):e2793. doi: 10.1097/MD.0000000000002793.

4) Lau CH, Wu X, Chung VC, Liu X, Hui EP, Cramer H, Lauche R, Wong SY, Lau AY, Sit RS, Ziea ET, Ng BF, Wu JC. (2016). Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care: Systematic Review and Meta-Analysis. Medicine (Baltimore). 95(9):e2901. doi: 10.1097/MD.0000000000002901.

 Keywords:
Systematic Review; Chinese Medicine (CM); Chinese Medicine (CM) Intervention; Cancer Palliative Care


系統評價; 系統性回顧; 中藥; 中醫藥治療; 癌症舒緩治療